Fabrication of nanocrystal forms of ᴅ-cycloserine and their application for transdermal and enteric drug delivery systems

• Hsuan-Ang Tsai,
• Tsai-Miao Shih,
• Theodore Tsai,
• Jhe-Wei Hu,
• Yi-An Lai,
• Jui-Fu Hsiao and
• Guochuan Emil Tsai

Beilstein J. Nanotechnol. 2024, 15, 465–474, doi:10.3762/bjnano.15.42

• studied over the last three decades, primarily due to its centrally active partial agonism of N-methyl-ᴅ-aspartate (NMDA) receptor [3][4][5][6][7][8][9][10][11][12]. Several researches indicated that DCS is a potential drug candidate to treat CNS disorders such as depression, schizophrenia, Alzheimer's

• disease, and post-traumatic stress disorder [13][14][15][16]. In general, solid dosage forms for oral administration are preferable for therapies against CNS disorders. Nevertheless, challenges persist with oral solid dosage forms, including issues of bioavailability and clinical efficacy [17]. On the

Ultrasensitive detection of cadmium ions using a microcantilever-based piezoresistive sensor for groundwater

• Dinesh Rotake,
• Anand Darji and
• Nitin Kale

Beilstein J. Nanotechnol. 2020, 11, 1242–1253, doi:10.3762/bjnano.11.108

• degeneration, diarrhea, osteoporosis, renal dysfunction, cancer, anemia, and neurological disorders such as Parkinson's disease or Alzheimer's disease [4][5]. The WHO has set a water contamination limit of 3 μg/L Cd(II) [6]. We conclude from the WHO limit that cadmium is hazardous, and smaller Cd

Strategy to discover full-length amyloid-beta peptide ligands using high-efficiency microarray technology

• Clelia Galati,
• Natalia Spinella,
• Lucio Renna,
• Danilo Milardi,
• Francesco Attanasio,
• Michele Francesco Maria Sciacca and
• Corrado Bongiorno

Beilstein J. Nanotechnol. 2017, 8, 2446–2453, doi:10.3762/bjnano.8.243

• well as the low sample consumption and the high potential for miniaturization, suggests that the proposed combination of peptide microarrays and highly efficient slides would be a very effective technology for molecule profiling in AD drug discovery. Keywords: Alzheimer's disease; florescence; high

Carbon nano-onions as fluorescent on/off modulated nanoprobes for diagnostics

• Stefania Lettieri,
• Marta d’Amora,
• Adalberto Camisasca,
• Alberto Diaspro and
• Silvia Giordani

Beilstein J. Nanotechnol. 2017, 8, 1878–1888, doi:10.3762/bjnano.8.188

• changes in the cells and tissues. Some of these events include cell proliferation and apoptosis [1], ion transport [2] and other cellular process and diseases such as cancer [3][4][5], Parkinson's, and Alzheimer's disease [6]. Despite the large number of nanotechnology platforms available to date for

Unraveling the neurotoxicity of titanium dioxide nanoparticles: focusing on molecular mechanisms

• Bin Song,
• Yanli Zhang,
• Jia Liu,
• Xiaoli Feng,
• Ting Zhou and
• Longquan Shao

Beilstein J. Nanotechnol. 2016, 7, 645–654, doi:10.3762/bjnano.7.57

• disorders with remarkable excitatory toxicity elements. Furthermore, the transcription of EAAT2 could be recovered by suppression of DNA methyltransferases [90]. Neurodegenerative diseases, such as Alzheimer's disease (AD) [91], Huntington’s disease (HD) [92], and amyotrophic lateral sclerosis (ALS) [93